摘要 |
A nozzle assembly for forming hollow fibers, particularly a "Z-fiber" having longitudinally oriented trabeculae with the fiber wall, is disclosed. The nozzle assembly contains a replaceable nozzle cap, a replaceable seal-guide, and a retractable central bore used to supply core material for the hollow fibers. The Z-fibers are particularly useful in enabling cells, solutes, or the like, to enter the fiber wall and move longitudinally into the center of the fiber wall. |
申请人 |
BROWN UNIVERSITY RESEARCH FOUNDATION, PROVIDENCE, R.I., US |
发明人 |
GENTILE, FRANK, T., PROVIDENCE, RI 02906, US;LYSAGHT, MICHAEL, J., E. GREENWICH, RI 02818,, US;WARNER, NICHOLAS, F., BELMONT, MA 02178, US |