发明名称 |
METHODS AND COMPOSITIONS FOR IDENTIFYING STREPTOCOCCUS CONTAINING A CYSTEINE PROTEASE OR FRAGMENT THEREOF |
摘要 |
Methods and compositions are provided for identifying a group A Streptococcus in any of a variety of physiological samples, such as blood, saliva, throat swabs, cerebrospinal fluid, brocheolar lavage material, and biopsy material. The compositions used include an extracellular cysteine protease or a fragment thereof, obtainable from S. pyogenes and containing at least one conserved epitope, or nucleic acid encoding the cysteine protease or fragment thereof. The compositions also find use in eliciting a protective immune response against a group A Streptococcus infection.
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申请公布号 |
CA2199867(A1) |
申请公布日期 |
1996.03.21 |
申请号 |
CA19952199867 |
申请日期 |
1995.09.13 |
申请人 |
BAYLOR COLLEGE OF MEDICINE |
发明人 |
MUSSER, JAMES A.;KAPUR, VIVEK |
分类号 |
C12N15/09;A61K39/00;A61K39/09;A61P7/00;A61P11/04;A61P13/12;A61P17/00;A61P29/00;A61P31/04;C07K7/06;C07K7/08;C07K14/315;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/52;C12N15/02;C12N15/57;C12P21/08;C12Q1/14;C12Q1/37;C12Q1/68;C12R1/46;G01N33/53;G01N33/566;G01N33/569;G01N33/573;G01N33/577;(IPC1-7):C12N15/57;A61K48/00;C12N5/02;C12N5/12;C07K16/40;A61K38/48;G01N33/543;A61K31/70 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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