发明名称 COMPOSITION AND METHOD FOR IMMUNOTHERAPY
摘要 An improved method for suppressing graft rejection in a host subject is disclosed. The method, as applied to allograft rejection, includes administering an immunosuppressant compound in an amount substantially below that required for effective suppression of allograft rejection, when the compound is administered alone. The suppressive effect of the compound is potentiated by administration of an ethanolic extract of Tripterygium wilfordii or a purified triptolide component thereof. The method as applied to xenograft rejection, includes administering an immunosuppressant drug, where the drug or the amount of drug administered is, by itself, ineffective to suppress xenograft rejection. Effective xenograft suppression is achieved by also administering an ethanolic extract of Tripterygium wilfordii or a purified triptolide component thereof.
申请公布号 WO9608262(A1) 申请公布日期 1996.03.21
申请号 WO1995US11645 申请日期 1995.09.15
申请人 PHARMAGENESIS, INC. 发明人 WIEDMANN, TIEN-WEN, TAO;JIN, RENLING;WANG, JIAN
分类号 A61K36/00;A61K36/37;A61K38/13;(IPC1-7):A61K35/78;A61K31/56;A61K31/505;A61K31/34 主分类号 A61K36/00
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