发明名称 TRIAZOLOPYRIDAZINES PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
摘要 Triazolopyridazine compound of formula (I), wherein R1 is hydrogen, halogen or alkyl; R2 is polycarbon alkyl or cycloalkyl; X is oxygen or S(O)p, wherein p is 0 to 2; Y is (i) a group of formula (a) wherein R3 and R4 are hydrogen or alkyl, or (ii) cycloalkylene or cycloalkylidene; R5 and R6 are H, alkyl, cycloalkyl, or may bind together for form a nitrogen-containing heterocyclic group; m and n are 0 to 4, or a salt thereof, possessing excellent antiasthmatic, anti-allergic, anti-PAF, eosinophil chemotaxis inhibiting activities.
申请公布号 CA2198019(A1) 申请公布日期 1996.03.21
申请号 CA19952198019 申请日期 1995.09.11
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 KAWANO, YASUHIKO;MIYAKE, AKIO;ASHIDA, YASUKO
分类号 A61K31/5025;C07D403/12;C07D487/04;(IPC1-7):C07D487/04;A61K31/50;A61K31/535 主分类号 A61K31/5025
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