A solid pharmaceutical dosage form containing codeine further includes a constituent which inhibits extraction of the codeine by filtration and solvent extraction without preventing release of the codeine in the digestive system. Suitable constituents include film forming agents, particularly cellulose derivatives at 1 to 10 % by weight, anionic surface active agents at 0.1 to 3 % by weight and ion exchange resins at 2 to 15 % by weight.
申请公布号
WO9608252(A1)
申请公布日期
1996.03.21
申请号
WO1995AU00601
申请日期
1995.09.14
申请人
SMITHKLINE BEECHAM PLC;CHAN, SHING, YUE;JAMES, DAVID, CHARLES;OWEN, PETER
发明人
CHAN, SHING, YUE;JAMES, DAVID, CHARLES;OWEN, PETER