| 摘要 |
PURPOSE: To simultaneously and efficiently culture bacillus bifidus and propionic acid bacteria, to raise antimicrobial activity and to improve amounts of bacillus bifidus and propionic acid bacteria multiplied and a multiplication rate by culturing bacillus bifidus and propionic acid bacteria in different culture tanks, respectively, while circulating culture solutions, respectively. CONSTITUTION: A bacillus bifidus such as Bifidobacterium bifidum and propionic acid bacteria such as Propionibacterium freudenreichii are cultured in different culture tanks, respectively. The culture solution during the culture of the bacillus bifidus is filtered by a filter membrane and added to the culture tank of the propionic acid bacteria. The culture solution in the culture tank of the propionic acid bacteria is filtered by a filter membrane and added to the culture tank of the bacillus bifidus. The culture is carried out while circulating both the culture solutions of both the culture tanks to simultaneously culture the bacillus bifidus and propionic acid bacteria. |
