发明名称 Thioformamide derivatives
摘要 The present invention provides a thioformamide derivative represented by the following general formula (I) or a pharmacologically acceptable salt thereof, which is highly safe, easy to use, and useful as an excellent hypotensive or heart disease remedy: <IMAGE> (I) wherein Y represents <IMAGE> <IMAGE> or the like [wherein R7 represents benzyloxy or the like; R11 and R12 each represent hydrogen, hydroxyl, benzoyloxy, benzyloxy, <IMAGE> (wherein R14 and R15 each represent hydrogen, benzyl or the like) or the like]; Z represents -CH2- or the like; A represents imidazolyl or imidazopyridyl which may have one or two substituents, or the like; R1 and R2 each represent hydrogen, lower alkyl or the like; and R3 and R4 each represent hydrogen, lower alkyl or the like.
申请公布号 US5498634(A) 申请公布日期 1996.03.12
申请号 US19950380589 申请日期 1995.01.30
申请人 EISAI CO., LTD. 发明人 KABASAWA, YASUHIRO;OZAKI, FUMIHIRO;ISHIBASHI, KEIJI;HASEGAWA, TAKASHI;OINUMA, HITOSHI;OGAWA, TOSHIAKI;ADACHI, HIDEYUKI;KATOH, HIROSHI;KODAMA, KOHTAROU;OHARA, HIDETO;MORI, NOBUYUKI;MINAMI, NORIO
分类号 C07D231/12;C07D233/92;C07D233/95;C07D471/04;(IPC1-7):A61K31/35;C07D309/08 主分类号 C07D231/12
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