PROCESS FOR THE SYNTHESIS OF 4-AMINO-1,2,4-(4H)TRIAZOLE DERIVATIVES

摘要

A process for preparing a 4-amino-1,2,4-(4H)triazole derivative composition having the formula wherein R is hydrogen or an alkyl group containing from 1 to about 10 carbon atoms, which alkyl group can be additionally substituted by one or more aryl, heteroaryl, hydroxy, or alkenyl substituents, comprising the step of reacting hydrazine or an aqueous hydrazine solution with a carboxylic acid having the formula RCO2H in the presence of an insoluble polymer containing acidic functional groups sufficiently strong to cause the reaction to proceed under mild conditions to produce a product of high yield and purity.