| 发明名称 |
Method of producing single-chain fv molecules |
| 摘要 |
The invention relates to a method of producing single-chain Fv molecules in eukaryotic cells, and to secretable sFv proteins having at least one non-naturally occurring glycosylation site. The single-chain Fv molecules produced by this method are biologically active and capable of being secreted from eukaryotic cells into the cell culture medium. |
| 申请公布号 |
AU3244695(A) |
申请公布日期 |
1996.03.07 |
| 申请号 |
AU19950032446 |
申请日期 |
1995.08.14 |
| 申请人 |
CREATIVE BIOMOLECULES, INC.;THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEP |
发明人 |
CAROLINA R JOST;DAVID M. SEGAL;JAMES S. HUSTON |
| 分类号 |
C12N15/09;A61K38/00;A61K39/395;A61P37/02;C07K16/00;C07K16/44;C07K16/46;C12P21/02;C12R1/91 |
主分类号 |
C12N15/09 |
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