发明名称 BIOLOGICALLY ACTIVE AND/OR ORIENTED CONJUGATES OF DENDRIMERS
摘要 Dendritic polymer conjugates which are composed of at least one dendrimer in association with at least one unit of a carried material, where the carrier material can be a biological response modifier, have been prepared. The conjugate can also have a target director present, and when it is present then the carried material may be a bioactive agent. Preferred dendritic polymers are dense star polymers, which have been complexed with biological response modifiers. These conjugates and complexes have particularly advantageous properties due to their unique characteristics.
申请公布号 PL311633(A1) 申请公布日期 1996.03.04
申请号 PL19950311633 申请日期 1995.03.07
申请人 THE DOW CHEMICAL CO;DENDRITECH INC;REGENTS OF THE UNIVERSITY OF MICHIGAN 发明人 TOMALIA DONALD A.;BAKER JAMES R.;BIELINSKA ANNA;BROTHERS HERBERT M.;CHENG ROBERTA C.;FAZIO MICHAEL J.;HEDSTRAND DAVID M.;JOHNSON JENNIFER A.;KAPLAN DONALD A.;KLAKAMP SCOTT L.;KRUPER WILLIAM J,JR;KUKOWSKA-LATALLO JOLANTA;MAXON BARTLEY D.;PIEHLER LARS.T.;TOMLINSON IAN A.;WILSON LARRY R.;YIN RUI
分类号 C12N15/02;A01N25/10;A61K;A61K31/70;A61K38/00;A61K39/385;A61K39/44;A61K45/00;A61K47/34;A61K47/48;A61K48/00;A61K49/00;A61K51/00;C07C211/29;C07C233/11;C07C237/20;C07K;C07K14/525;C07K14/535;C07K14/54;C07K14/555;C07K17/06;C07K17/08;C08G73/00;C08G83/00;C08L101/00;C12N;C12N5/10;C12N15/09;C12N15/57;C12N15/87;C12P21/02;C12P21/08;C12R1/91;(IPC1-7):A61K47/48 主分类号 C12N15/02
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