发明名称 LIPOSOME-ENCAPSULATED TAXOL, ITS PREPARATION AND ITS USE
摘要 The fields of application of the invention are medicine and the pharmaceutical industry. The aim of the invention is to produce liposome-encapsulated taxol with a high taxol concentration and high stability and hence a high therapeutic effect. The invention involves the development of specific forms of taxol encapsulation and the use of these, optionally in combination with other substances, in the treatment of various types of tumour. The liposome-encapsulated taxol is characterized in that it is prepared by high-pressure homogenization or by aerosol formation. An exemple is the use in combination with liposome-encapsulated carboplatinum in aerosol form in the treatment of lung metastases.
申请公布号 WO9605821(A1) 申请公布日期 1996.02.29
申请号 WO1995DE01163 申请日期 1995.08.18
申请人 MAX-DELBRUECK-CENTRUM FUER MOLEKULARE MEDIZIN;RESZKA, REGINE;BRANDL, MARTIN;FICHTNER, IDUNA;WARNKE, GERNOT 发明人 RESZKA, REGINE;BRANDL, MARTIN;FICHTNER, IDUNA;WARNKE, GERNOT
分类号 A61K9/00;A61K9/127;A61K31/335;A61K31/337;A61K31/555;C07D493/00 主分类号 A61K9/00
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