摘要 |
<p>Object: to provide an erythromycin derivative having a potent interleukin-5 production inhibitory effect. Constitution: an interleukin-5 production inhibitor containing as the active ingredient an erythromycin derivative, such as 3-0-(4-biphenyl)acetyl-5-0-desosaminyl-6-0-methylerythronolide A 11,12-cyclic carbonate or 3-0-(2-nitro-3,4,5,6-tetrafluoro)phenyl-5-0-desosaminyl-6-0-methylerythronolide A, or a medicinally acceptable acid-addition salt thereof.</p> |