| 摘要 |
Compounds of formula (I), wherein n is 1, 2 or 3; R<1> and R<2> each independently represent hydrogen, C1-6alkyl, C3-6cycloalkyl, or C3-6cycloalkylC1-4alkyl; p and q independently represent 0-4; X represents O, S, NH or, provided that the sum of p and q is at least 1, a bond; and Ar represents phenyl substituted by -Y-CR<3>R<4>-Ph, where Y is oxygen or a bond, R<3> and R<4> are indenpendently, H, methyl or ethyl, provided that R<3> and R<4> are not both H, and Ph is optionally substituted phenyl; and salts thereof are calcium channel antagonists useful in the treatment of ischaemic conditions e.g. stroke. |
