发明名称 |
BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS |
摘要 |
Guanidine derivatives of formula (I) wherein R<1> is hydrogen, hydroxy(lower)alkyl, protected hydroxy(lower)alkyl, acyl(lower)alkoxy, acyl(lower)alkenyl, or acyl, and R<2> is ar(lower)alkenyl; aryl substituted with two suitable substituents; indenyl, indanyl, dihydrobenzocycloheptenyl, di(or tetra or hexa or octa or deca)hydronaphthyl, cyclopentenyl, dihydrothienyl, dihydrofuryl or heterobicyclic group, each of which may have suitable substituent(s); lower alkylthienyl; mono(or di)halothienyl; mono(or di or tri)halo(lower)alkylthienyl; acylthienyl; halofuryl; or mono(or di or tri)halo(lower)alkylfuryl; and a pharmaceutically acceptable salt thereof, which is useful as a medicament. |
申请公布号 |
WO9604241(A2) |
申请公布日期 |
1996.02.15 |
申请号 |
WO1995JP01479 |
申请日期 |
1995.07.25 |
申请人 |
FUJISAWA PHARMACEUTICAL CO., LTD.;KUNO, ATSUSHI;MIZUNO, HIROAKI;YAMASAKI, KUMI;INOUE, YOSHIKAZU |
发明人 |
KUNO, ATSUSHI;MIZUNO, HIROAKI;YAMASAKI, KUMI;INOUE, YOSHIKAZU |
分类号 |
C07D295/14;A61K31/165;A61K31/185;A61K31/275;A61K31/357;A61K31/36;A61K31/38;A61K31/381;A61K31/40;A61K31/435;A61K31/47;A61K31/472;A61K31/495;A61P9/00;A61P9/10;A61P13/02;A61P15/00;C07C279/22;C07D209/08;C07D215/14;C07D217/02;C07D217/16;C07D241/42;C07D263/56;C07D295/13;C07D295/22;C07D307/46;C07D307/56;C07D307/79;C07D307/80;C07D307/82;C07D311/58;C07D311/96;C07D317/54;C07D317/58;C07D321/00;C07D333/22;C07D333/28;C07D333/34;C07D333/36;C07D333/54;C07D333/56;C07D333/62;C07D471/04 |
主分类号 |
C07D295/14 |
代理机构 |
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代理人 |
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地址 |
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