NOVEL BENZIMIDAZOLE DERIVATIVES

摘要

The invention provides compounds having structure (I), wherein each of R1, R2, R3 and R9 is independently H; straight chain, branched, substituted or unsubstituted alkyl, alkenyl or alkynyl; cycloalkyl, cycloalkenyl; acyl; phenyl; substituted phenyl or heteroaryl; wherein each R4, R5 and R6 is independently H; F; Cl; Br; I; straight chain, branched, substituted or unsubstituted alkyl, alkenyl or alkynyl; cycloalkyl; cycloalkenyl; phenyl; unsubstituted phenyl; heteroaryl; etc. and wherein each R8 is independently H; straight, branched, substituted or unsubstituted alkyl, alkenyl or alkynyl; phenyl or substituted phenyl. These compounds are selective for cloned human alpha 2 receptors and are useful as analgesic, sedative or anaesthetic agents.