| 发明名称 |
INTRACELLULAR EXPRESSION OF CARBOXYPEPTIDASE G2 IN ENZYME PRODRUG THERAPY |
| 摘要 |
The invention provides a two-component system for gene-directed enzyme prodrug therapy which comprises: (a) a vector which encodes a carboxypeptidase which is expressed within a cell; and (b) a prodrug which can be converted into an active drug by said carboxypeptidase, useful in the treatment of tumours. |
| 申请公布号 |
WO9603151(A2) |
申请公布日期 |
1996.02.08 |
| 申请号 |
WO1995GB01783 |
申请日期 |
1995.07.27 |
| 申请人 |
CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED;SPRINGER, CAROLINE, JOY;MARAIS, RICHARD |
发明人 |
SPRINGER, CAROLINE, JOY;MARAIS, RICHARD |
| 分类号 |
C12N15/09;A61K31/13;A61K31/35;A61K31/44;A61K35/76;A61K38/46;A61K38/48;A61K38/55;A61K45/00;A61K47/48;A61K48/00;A61P35/00;A61P43/00;C07K14/71;C12N5/10;C12N9/12;C12N9/48;C12N9/52;C12N15/57;C12R1/91 |
主分类号 |
C12N15/09 |
| 代理机构 |
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