METHOD FOR SCREENING COMPOUND LIBRARIES

摘要

A method for screening a compound library provided on solid phase, which method comprises releasing a proportion of the library from the solid phase into distinct zones of an assay medium, performing a proximity screening assay with a biological of interest within the medium, identifying active zone(s) in the assay medium and determining the identity of active member(s) of the library by reference to the corresponding compound(s) still bound to the solid phase.