发明名称 |
INDOLIZINE SPLA2 INHIBITORS |
摘要 |
A class of novel indolizine-1-functional compounds and indolizine-3-functional compounds is disclosed together with the use of such indolizine compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock. The compounds are indolizine-1-acetamides, indolizine-1-acetic acid hydrazides, indolizine-1-glyoxylamides, indolizine-3-acetamides, indolizine-3-acetic acid hydraxides, and indolizine-3-glyoxylamides.
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申请公布号 |
CA2195570(A1) |
申请公布日期 |
1996.02.08 |
申请号 |
CA19952195570 |
申请日期 |
1995.07.20 |
申请人 |
ELI LILLY AND COMPANY;SHIONOGI & CO., LTD. |
发明人 |
DILLARD, ROBERT DELANE;HAGISHITA, SANJI;OHTANI, MITSUAKI |
分类号 |
A61K31/435;A61P1/00;A61P11/00;A61P27/16;A61P29/00;A61P31/04;A61P37/08;A61P43/00;C07D471/04;C07F9/6561;(IPC1-7):C07D471/04;C07D519/00;A61K31/495;A61K31/53;C07F9/656;A61K31/675 |
主分类号 |
A61K31/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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