发明名称 |
Novel 3-(substituted methyl)-4-oxa-1-azabicyclo[3.2.0] heptan-7-one derivatives useful as antitumor agents |
摘要 |
PCT No. PCT/GB95/00024 Sec. 371 Date Aug. 5, 1998 Sec. 102(e) Date Aug. 5, 1998 PCT Filed Jan. 6, 1995 PCT Pub. No. WO95/18807 PCT Pub. Date Jul. 13, 1995The present invention is based on the discovery that certain 3-(substituted methyl)-4-oxa-1-azabicyclo[3.2.0]heptan-7-one derivatives of formula I or a pharmaceutically acceptable salt thereof are useful as antitumor agents against sensitive and resistant tumor cells. Wherein X is NH or O, and R is defined in the specification. |
申请公布号 |
ZA9500106(B) |
申请公布日期 |
1996.02.07 |
申请号 |
ZA19950000106 |
申请日期 |
1995.01.09 |
申请人 |
TAIHO PHARMACEUTICAL CO.;SYNPHAR LABORATORIES, INC. |
发明人 |
RAJESHWAR SINGH;TOMOHIRO YAMASHITA;CHARLES FIAKPUI;GEORGE THOMAS;CHAN HA;HIROSHI MATSUMOTO;TOSHIO OTANI;SHINJI OIE;RONALD MICETICH |
分类号 |
A61K31/42;A61P35/00;C07D503/00 |
主分类号 |
A61K31/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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