| 摘要 |
Process for preventing activation of enzyme systems such as coagulation and activation of complement system or bradykinin system in extracorporeal blood circulation in haemodialysis and similar procedures, by means of sequential anticoagulation, wherein in the first 15 to 30 minutes of haemodialysis or of procedure which is similar to haemodialysis, sodium citrate or nafamostat mesylate, preferably sodium citrate, is given into a dialysis line as anticoagulant, then adding of a heparin-free anticoagulant is stopped and there is started with the addition of heparin in the conventional total dose, this addition being carried out till the end of dialysis, is disclosed. By the process according to the invention a universal routine haemodialysis or a similar procedure, is made possible without further adaptations to the kind of patients.
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