发明名称 |
Method for forming controlled release polymeric substrate |
摘要 |
A method for forming a controlled release polymeric substrate is provided by contacting a polymeric substrate with a liquid mixture containing a cross-linking agent at least partially soluble therein comprising water and an organic liquid, for a period of time and at a temperature and concentration of the agent sufficient for the agent to penetrate the substrate to form cross-linking bridges in the substrate in a decreasing concentration gradient beneath the surface.
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申请公布号 |
US5487895(A) |
申请公布日期 |
1996.01.30 |
申请号 |
US19930106342 |
申请日期 |
1993.08.13 |
申请人 |
VITAPHORE CORPORATION |
发明人 |
DAPPER, GREGORY S.;YAMAMOTO, RONALD K. |
分类号 |
A61K9/16;A61K9/50;(IPC1-7):A61K39/00;A61K9/52 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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