发明名称 |
PLATELET-ENDOTHELIAL CELL ADHESION MOLECULE-1 COMPOSITIONS AND METHODS |
摘要 |
Novel, substantially isolated isoforms of human platelet-endothelial cell adhesion molecule-1's, DNAs coding for transcripts that encode the novel isoforms and others, including a previously identified soluble isoform, methods of using such DNAs to make isoforms by expressing the DNA's, and promoter segments controlling transcription of human platelet-endothelial cell adhesion molecule-1 genes are provided. The novel isoforms differ from the complete human platelet-endothelial cell adhesion molecule-1's in lacking one or more segments near the C-terminus encoded by exons 10-15 of the genes for the full length molecules and arise in vivo from alternative splicing of the transcript from the genes.
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申请公布号 |
WO9601271(A1) |
申请公布日期 |
1996.01.18 |
申请号 |
WO1995US08268 |
申请日期 |
1995.07.05 |
申请人 |
THE BLOOD CENTER RESEARCH FOUNDATION, INC. |
发明人 |
NEWMAN, PETER, J.;GUMINA, RICHARD, J.;KIRSCHBAUM, NANCY |
分类号 |
C12N15/09;A61K38/00;A61K48/00;A61P9/10;A61P29/00;C07H21/02;C07H21/04;C07K14/47;C07K14/705;C12N15/12;C12P21/02;C12Q1/68;(IPC1-7):C07H21/04;C07K1/00;C07K14/00;C12N15/00;C12N15/11;C12P21/04;C12P21/06 |
主分类号 |
C12N15/09 |
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