发明名称 |
Process for the preparation of 6,7-diacyl-7-deacteylforskolin derivatives |
摘要 |
This invention relates to a process for the preparation of a 6,7-diacyl-7-deacetylforskolin derivative represented by the general formula: <IMAGE> (I) wherein R1 and R2 each stands for an acyl group and R3 stands for an aliphatic group having 2 to 3 carbon atoms, which comprises eliminating the acyl group at position 1 in a 1,6,7-triacyl-7-deacetylforskolin derivative represented by the general formula: <IMAGE> (III) wherein R1, R2 and R3 are as defined above, by solvolysis. The compound of the formula (I) is expected as medicine.
|
申请公布号 |
US5484954(A) |
申请公布日期 |
1996.01.16 |
申请号 |
US19940179826 |
申请日期 |
1994.01.19 |
申请人 |
NIPPON KAYAKU KABUSHIKI KAISHA |
发明人 |
TATEE, TOCHIRO;SHIOZAWA, AKIRA;YAMAMOTO, HIROTAKA;ICHIKAWA, YUH-ICHIRO;NARITA, AYA |
分类号 |
C07D311/92;(IPC1-7):C07D311/92 |
主分类号 |
C07D311/92 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|