发明名称 CROSS-REACTING MONOCLONAL ANTIBODIES SPECIFIC FOR E-SELECTIN AND P-SELECTIN
摘要 The invention provides monoclonal antibodies that specifically bind to Pselectin and to E-selectin. Humanized monoclonal antibodies also are disclosed. Many of the antibodies block the functional interactions of Pselectin and E-selectin with their respective counterreceptors.
申请公布号 CA2191870(A1) 申请公布日期 1995.12.21
申请号 CA19952191870 申请日期 1995.06.07
申请人 PROTEIN DESIGN LABS, INC. 发明人 BERG, ELLEN L.
分类号 G01N33/53;A61K38/00;A61K39/395;A61P9/08;A61P9/10;A61P11/00;A61P17/00;A61P29/00;A61P31/04;A61P37/00;A61P37/06;A61P43/00;C07K16/18;C07K16/28;C07K16/46;C12N5/10;C12N15/00;C12N15/09;C12N15/13;C12P21/08;G01N33/577;(IPC1-7):C12N15/13;G01N33/566 主分类号 G01N33/53
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