SOLID ANTACID AND PROCESS FOR PRODUCING THE SAME

摘要

A pharmaceutical composition which has excellent effects of promptly neutralizing the initial pH immediately after the administration without excessively increasing it, and of sustaining the optimum pH; which is useful for providing a solid antacid which exhibits excellent antacid effects based on the above effects; and which comprises, as antacid ingredients for a solid antacid, a low neutralizing capacity antiacid (having an initial pH less than 6 when tested in accordance with the modified Fuchs method using 30 ml of 0.05N hydrochloric acid and single dosage; e.g., dried aluminum hydroxide gel) and a high neutralizing capacity antiacid (having the initial pH of at least 6 when tested as described above; e.g., magnesium hydroxide) coated with a pH-independent and water-insoluble polymer base (e.g., an aqueous dispersion of ethyl cellulose); and a production process thereof.