发明名称 |
Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment |
摘要 |
The present invention is directed to novel taxanes useful as chemotherapeutic agents or their precursors. Processes for preparing the novel taxanes include coupling reactions, in the presence of a base, of baccatin of formula (III) or (IV) <IMAGE>rmula (V). <IMAGE> (V) The invention also provides pharmaceutical compositions including the novel taxanes and method for treatment of certain cancers with these new compounds.
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申请公布号 |
US5475011(A) |
申请公布日期 |
1995.12.12 |
申请号 |
US19930040189 |
申请日期 |
1993.03.26 |
申请人 |
THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK;INDENA SPA |
发明人 |
OJIMA, IWAO;BOMBARDELLI, EZIO |
分类号 |
A61K31/00;A61K31/335;A61K31/337;A61P35/00;C07D205/08;C07D305/14;C07F7/18;(IPC1-7):A61K31/445;C07D305/00 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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