发明名称 |
EPOXYSUCCINIC ACID DERIVATIVES, THEIR PRODUCTION AND USE |
摘要 |
The present invention relates to a compound of formula (I), wherein R1 stands for an optionally esterified or amidated carboxyl group, X stands for an optionally substituted divalent hydrocarbon residue, R2 stands for hydrogen or an optionally substituted hydrocabon residue, R3 stands for an alkyl group which is substituted with a group bonded through O or S(O)n wherein n is 0, 1 or 2, with a proviso that when the partial structural formula: -NH-X-CO- is leucine residue, R3 is not 3-hydroxy-3-methylbutyl group nor 4-hydroxy-3-methylbutyl group, or a salt thereof, which is useful as prophylactic and therapeutic agents of bone diseases and as inhibitory agents of thiol protease.
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申请公布号 |
CA2190151(A1) |
申请公布日期 |
1995.12.07 |
申请号 |
CA19952190151 |
申请日期 |
1995.05.25 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
TSUBOTANI, SHIGETOSHI;TAKIZAWA, MASAYUKI;MIZOGUCHI, JUNJI |
分类号 |
C07D303/48;(IPC1-7):C07D303/48;C07D405/12;C07D407/12;C07D409/12;C07D413/12;C07D417/12;A61K31/33;A61K31/665 |
主分类号 |
C07D303/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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