发明名称 |
OXATHIOLANES, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
摘要 |
The present invention pertains to the field of organic chemistry, and particularly therapeutic chemistry. The invention provides cis-form 5-(cytosinyl-1) 1,3-oxathiolanes of general formula (I), wherein R is an acyl or aralkoyl radical, derivatized from a nitrogen monocyclic or bicyclic heterocycle, and the hydroxymethyl group in position 2 is in cis position in relation to the plane defined by positions 2 and 5. The compounds of general formula (I) are useful as active ingredients in pharmaceutical compositions, particularly with antiviral activity. |
申请公布号 |
WO9532200(A1) |
申请公布日期 |
1995.11.30 |
申请号 |
WO1995FR00683 |
申请日期 |
1995.05.24 |
申请人 |
LABORATOIRE LAPHAL;CHARVET-FAURY, ANNE-SOPHIE;CAMPLO, MICHEL;KRAUS, JEAN-LOUIS |
发明人 |
CHARVET-FAURY, ANNE-SOPHIE;CAMPLO, MICHEL;KRAUS, JEAN-LOUIS |
分类号 |
A61K31/44;A61K31/465;A61K31/47;A61K31/506;A61K31/513;A61P31/12;A61P37/04;C07D211/00;C07D239/00;C07D327/00;C07D411/14;C07F7/18 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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