| 发明名称 |
Recombinant DNA encoding PDGF A-chain polypeptides. |
| 摘要 |
DNA encoding two forms of PDGF A-chain polypeptide, the construction of expression vectors for expressing such DNA in yeast and mammalian cells, and the expression of such DNA in yeast and mammalian cells to produce active PDGF A-chain homodimer and active PDGF A-chain/B-chain heterodimer are disclosed. |
| 申请公布号 |
EP0682110(A1) |
申请公布日期 |
1995.11.15 |
| 申请号 |
EP19950105415 |
申请日期 |
1988.04.22 |
| 申请人 |
CHIRON CORPORATION |
发明人 |
HELDIN, CARL-HENRIK, LUDWIG INST. FOR;BETSHOLTZ, CHRISTER;WESTERMARK, BENGT;KNOTT, TIMOTHY J.;SCOTT, JAMES, DIRECTOR OF MEDICINE;BELL, GRAEME I.;RALL, LESLIE |
| 分类号 |
A61K38/00;A61P17/00;A61P43/00;C07K1/20;C07K14/00;C07K14/49;C07K14/52;C12N1/16;C12N5/10;C12N9/02;C12N15/09;C12N15/62;C12N15/81;C12N15/85;C12P21/02;C12R1/91 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
