Intermediates for the preparation of cyclic urea

摘要

This invention relates to novel compounds and derivatives thereof containing a trioxepane protected diol in addition to a hydrazone, hydrazine, amine, or cyclic urea moiety; methods for the preparation of said compounds; and the use of said compounds in processes to prepare human immunodeficiency virus (HIV) protease inhibitors which effectively inhibit HIV. The novel compounds provided by this invention have the formulae: <IMAGE> (II) <IMAGE> (III) <IMAGE> (IV) <IMAGE> (V) wherein the substituents are as defined herein.