Co-administration of S-adenosyl-L-methionine to reduce the nephrotoxicity of cisplatin therapy

摘要

PCT No. PCT/JP93/01250 Sec. 371 Date Apr. 7, 1994 Sec. 102(e) Date Apr. 7, 1994 PCT Filed Sep. 3, 1993 PCT Pub. No. WO94/05299 PCT Pub. Date Mar. 17, 1994.A pharmaceutical composition for use as a nephrotoxicity alleviator for alleviating the nephrotoxicity caused by a drug administered into the living organism, which composition contains S-adenosyl-L-methionine or a salt thereof as an active ingredient is provided. Also provided is a pharmaceutical composition for use as an agent for potentiating the antitumor activity of platinum complex compounds, which composition contains S-adenosyl-L-methionine as an active ingredient.