发明名称 |
Tumor suppressor gene and methods for detection of cancer, monitoring of tumor progression and cancer treatment |
摘要 |
A gene that encodes an inhibitor of CDK4 has been discovered and its genomic nucleotide sequence has been identified. Susceptibility to certain cancers has been shown to be causatively related to the deletion of, or polymorphisms in, the CDK4I gene. The invention is therefore directed to the gene (CDK4I), the inhibitor protein, as well as therapeutic and diagnostic methods which utilize both the CDK4I gene and the CDK4I protein. |
申请公布号 |
AU2385095(A) |
申请公布日期 |
1995.11.10 |
申请号 |
AU19950023850 |
申请日期 |
1995.04.12 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
DENNIS A. CARSON;TSUTOMU NOBORI |
分类号 |
C12N15/09;A61K38/00;A61P35/00;C07H21/04;C07K14/47;C07K14/82;C07K16/18;C07K16/32;C12P21/02;C12P21/08;C12Q1/02;C12Q1/68;G01N33/53 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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