| 发明名称 |
NOVEL ACYCLIC AND CYCLIC AMIDES AS NEUROTRANSMITTER RELEASE ENHANCERS |
| 摘要 |
This invention relates to compounds of formula (IA), (IB), (IC) or (ID), wherein m, X, Z, R<2>, R<3>, R<4>, R<5>, R<6>, R<14> and the dotted lines are as defined below, their pharmaceutically acceptable salts, pharmaceutical compositions containing them and methods of using them to treat Alzheimer's disease, age-associated memory impairment, Parkinson's disease and other central nervous system disorders. The claimed compounds have the ability to enhance the release of neurotransmitters such as acetylcholine, dopamine and serotonin. |
| 申请公布号 |
WO9529909(A1) |
申请公布日期 |
1995.11.09 |
| 申请号 |
WO1995IB00189 |
申请日期 |
1995.03.20 |
| 申请人 |
PFIZER INC.;VOLKMANN, ROBERT, A.;JASYS, VYTAUTAS, J.;BRIGHT, GENE, M.;VILLALOBOS, ANABELLA;SEYMOUR, PATRICIA, A. |
发明人 |
VOLKMANN, ROBERT, A.;JASYS, VYTAUTAS, J.;BRIGHT, GENE, M.;VILLALOBOS, ANABELLA;SEYMOUR, PATRICIA, A. |
| 分类号 |
C07D213/56;A61K31/00;A61K31/215;A61K31/341;A61K31/381;A61K31/395;A61K31/415;A61K31/4164;A61K31/4166;A61K31/4178;A61K31/4192;A61K31/4196;A61K31/42;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4418;A61K31/4427;A61K31/443;A61K31/4439;A61K31/495;A61K31/4965;A61K31/497;A61K31/505;A61K31/506;A61P25/00;A61P25/16;A61P25/18;A61P25/22;A61P25/28;A61P25/30;A61P43/00;C07C233/06;C07D213/20;C07D231/12;C07D233/76;C07D239/26;C07D241/12;C07D249/04;C07D249/08;C07D261/08;C07D307/16;C07D307/54;C07D333/24;C07D401/06;C07D401/14;C07D405/06;C07D405/14;C07D413/06;(IPC1-7):C07D401/06 |
主分类号 |
C07D213/56 |
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