A sustained release oral solid dosage form of metoprolol pharmaceutical formulation includes a sustained release excipient including a gelling agent, an inert pharmaceutical diluent, a cationic cross-linking agent. The formulation provides release of metoprolol for at least about 24 hours. Methods of preparation and methods of treatment using the preparations of the invention are also disclosed.
申请公布号
WO9528917(A1)
申请公布日期
1995.11.02
申请号
WO1995US04118
申请日期
1995.04.06
申请人
EDWARD MENDELL CO., INC.;BAICHWAL, ANAND, R.;MCCALL, TROY, W.