发明名称 |
Vectors and compounds for expression of glycosylation mutants of human protein C |
摘要 |
A method for the recombinant production of forms of human protein C with higher activity is described. These forms differ from native protein C in their increased amidolytic and functional activities and novel carbohydrate structures. DNA compounds, vectors, and transformants useful in the method are also disclosed.
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申请公布号 |
US5460953(A) |
申请公布日期 |
1995.10.24 |
申请号 |
US19930093217 |
申请日期 |
1993.09.09 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
GERLITZ, BRUCE E.;GRINNELL, BRIAN W. |
分类号 |
A61K38/43;A61K38/00;A61P7/02;C07K14/00;C12N1/21;C12N5/10;C12N9/64;C12N15/09;C12N15/12;C12R1/19;(IPC1-7):C12N9/64;C12N15/57;C12N15/70;C12N15/79 |
主分类号 |
A61K38/43 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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