METHODS OF USING IRON CHELATING COMPOUNDS TO REDUCE FREE RADICAL DAMAGE IN MAMMALS

摘要

The subject invention involves a method of reducing free radical damage in mammals comprising administering to a mammal a composition comprising a safe and effective amount of a compound selected from 1-phenyl-1,2-propanedione-2-oxime, benzoylacetone, piroctone, 2-furildioxime, 2-furilmonoxime, diethyldithiocarbamic acid, deferoxamine and 1,2-dimethyl-3-hydroxy-pyrid-4-one, or a pharmaceutically acceptable salt thereof, or mixtures of the subject compounds and/or their salts.