发明名称 |
Antimicrobial peptides antibodies and nucleic acid molecules from bovine neutrophils |
摘要 |
The present invention provides a new family of cysteine-rich antimicrobial peptides isolated from bovine neutrophils herein named beta defensins. Thirteen structurally homologous peptides were purified to homogeneity from a granule-rich cytoplasmic fraction of purified blood neutrophils. These antimicrobial compounds are useful in human and veterinary medicine, and as agents in agricultural, food science, and industrial applications.
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申请公布号 |
US5459235(A) |
申请公布日期 |
1995.10.17 |
申请号 |
US19930033873 |
申请日期 |
1993.03.19 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
SELSTED, MICHAEL E.;CULLOR, JAMES S. |
分类号 |
C12N15/09;A61K38/00;A61K39/395;A61P31/04;C07K14/47;C07K16/18;C12N5/02;C12P21/02;C12P21/08;(IPC1-7):A61K38/00;C07H17/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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