发明名称 |
Treatment of atherosclerosis with angiotensin ii receptor blocking imidazoles |
摘要 |
A method of treatment for atherosclerosis and/or reducing cholesterol using an angiotensin II antagonist. This method of treatment can be used in conjunction with the treatment of hypertension. Substituted imidazoles such as <IMAGE> are useful as angiotensin II receptor antagonists for this method of treatment. A method of treatment for atherosclerosis and/or reducing cholesterol using an angiotensin II receptor antagonist in combination with an HMG-Co A reductase inhibitor. A method of treatment for atherosclerosis and/or reducing cholesterol using an angiotensin II receptor antagonist in combination with an HMG-Co A reductase inhibitor and an angiotensin converting enzyme inhibitor. Also within the scope of this invention are pharmaceutical compositions for this method of use. |
申请公布号 |
AU2127995(A) |
申请公布日期 |
1995.10.17 |
申请号 |
AU19950021279 |
申请日期 |
1995.03.24 |
申请人 |
MERCK & CO., INC. |
发明人 |
EDWARD B NELSON;CHARLES S. SWEET |
分类号 |
C07D233/64;A61K31/35;A61K31/351;A61K31/40;A61K31/415;A61K31/4178;A61K31/44;A61K31/4418;A61K45/00;A61P3/06;A61P9/10;A61P9/12;A61P43/00;C07C69/24;C07D207/16;C07D213/26;C07D233/68;C07D233/90;C07D309/30;C07D403/10 |
主分类号 |
C07D233/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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