发明名称 Treatment of atherosclerosis with angiotensin ii receptor blocking imidazoles
摘要 A method of treatment for atherosclerosis and/or reducing cholesterol using an angiotensin II antagonist. This method of treatment can be used in conjunction with the treatment of hypertension. Substituted imidazoles such as <IMAGE> are useful as angiotensin II receptor antagonists for this method of treatment. A method of treatment for atherosclerosis and/or reducing cholesterol using an angiotensin II receptor antagonist in combination with an HMG-Co A reductase inhibitor. A method of treatment for atherosclerosis and/or reducing cholesterol using an angiotensin II receptor antagonist in combination with an HMG-Co A reductase inhibitor and an angiotensin converting enzyme inhibitor. Also within the scope of this invention are pharmaceutical compositions for this method of use.
申请公布号 AU2127995(A) 申请公布日期 1995.10.17
申请号 AU19950021279 申请日期 1995.03.24
申请人 MERCK & CO., INC. 发明人 EDWARD B NELSON;CHARLES S. SWEET
分类号 C07D233/64;A61K31/35;A61K31/351;A61K31/40;A61K31/415;A61K31/4178;A61K31/44;A61K31/4418;A61K45/00;A61P3/06;A61P9/10;A61P9/12;A61P43/00;C07C69/24;C07D207/16;C07D213/26;C07D233/68;C07D233/90;C07D309/30;C07D403/10 主分类号 C07D233/64
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