TUMOR NECROSIS FACTOR INHIBITORS

摘要

Peptides that consist of 4 to 25 amino acids and that inhibit tumor necrosis factor-alpha activity are disclosed. Methods of inhibiting tumor necrosis factor activity are disclosed. The methods comprise contacting tumor necrosis factor alpha with a peptide that comprises an amino acid sequence that consists of 4 to 25 amino acids and that inhibits tumor necrosis factor-alpha activity are disclosed. Methods of treating animals suspected of suffering from a disease or disorder mediated by tumor necrosis factor-alpha activity are disclosed. The methods comprise the step of administering to the individual a therapeutically effective amount of a peptide that comprises an amino acid sequence that consists of 4 to 25 amino acids and that inhibits tumor necrosis factor-alpha activity.