发明名称 |
Recombinant defective virus contg. DNA encoding glutamate decarboxylase |
摘要 |
Recombinant defective virus contg. a DNA sequence (I) encoding a protein (II) with glutamate decarboxylase (GAD) activity, is new. Also new are:(1) a virus as above where the DNA is cDNA or gDNA which is under the control of a LTR-RSV promoter (which can be expressed in the majority of nerve cells);(2) a pharmaceutical compsn. contg. the virus;(3) mammalian cells infected with this virus, and(4) implants contg. these cells and an extracellular matrix.
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申请公布号 |
FR2717823(A1) |
申请公布日期 |
1995.09.29 |
申请号 |
FR19940003411 |
申请日期 |
1994.03.23 |
申请人 |
RHONE POULENC RORER SA;ROUSSY INSTITUT GUSTAVE;CENTRE NAL RECHERC SCIENTIFIQUE |
发明人 |
JULIEN JEAN FRANCOIS;ROBERT JEAN-JACQUES;GEOFFROY MARIE-CLAUDE;PERRICAUDET MICHEL;VIGNE EMMANUELLE;MALLET JACQUES |
分类号 |
A61K38/00;A61K48/00;C12N9/88;(IPC1-7):C12N7/01;C12N5/10;A61L27/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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