摘要 |
<p>The present invention relates to a DNA expression vector comprising a Tαl α-tubulin promoter operatively linked upstream to a marker gene sequence relative to the direction of transcription in a eukaryotic expression vector adapted to be introduced into a mammal, or ancestor of the mammal at an embryonic stage, and said promoter is controlling transcription of the marker gene. The present invention also relates to a method for testing material suspected of promoting neurogenesis and neuronal growth which comprises exposing a transgenic mammal according to the present invention to said material and detecting said expressed marker gene as an indication of neurogenesis and neuronal growth.</p> |