| 摘要 |
<p>A ruthenium-optically active phosphine complex has, as a ligand, BICHEP, i.e., 2,2 min -bis(dicyclohexyl-phosphino)-6,6 min dimethyl-1,1 min -biphenyl represented by formula (I): <CHEM> Specific examples of the complex are: [Ru(BICHEP](OAc)2 (wherein Ac is an acetyl group) [Ru(BICHEP)(p-cymene)I]I [Ru(BICHEP)(p-cymene)Cl]Cl (Ru2Cl4(BICHEP)2]NEt3 (wherein Et is an ethyl group). Preparation is by the processes of US-4739084, EP-A-366,390 and US-4691037. Preparation of optically active BICHEP is described. The complex is used to catalyse assymmetric syntheses, e.g. of an optically active carboxylic acid or ester in high purity and good yield.</p> |
