FIBROBLAST GROWTH FACTOR-10

摘要

Disclosed are human FGF-10 polypeptides and DNA (RNA) encoding such FGF-10 polypeptides. Also provided is a procedure for producing such polypeptide by recombinant techniques. Also disclosed are methods for utilizing such polypeptide for stimulating re-vascularization, for treating wounds and prevent neuronal damage. Antagonists against such polypeptides and their use as a therapeutic to prevent abnormal cellular proliferation, hyper-vascular diseases and epithelial lens cell proliferation are also disclosed. Diagnostic methods for detecting mutations in the FGF-10 coding sequence and alterations in the concentration of FGF-10 protein in a sample derived from a host are also disclosed.