| 摘要 |
<p>Quinoline derivatives of formula (I), wherein R1 is hydrogen, halogen, lower alkyl, etc., R2 is hydroxy or protected hydroxy, R3 is lower alkyl, etc., (a) is a group of formula (i) (in which R4 is lower alkyl, lower alkenyl, lower alkoxy(lower)alkyl, cyclo(lower)alkyl or lower alkoxy(lower)alkoxy(lower)-alkyl, and R5 is aryl which may have suitable substitutent(s) or heterocyclic group), etc., R7 is hydrogen or halogen, R8 is hydrogen or lower alkyl, etc., and Z is O or S, and a pharmaceutically acceptable salt thereof which are useful as a medicament.</p> |
