发明名称 |
NOVEL CARBOCYCLIC COMPOUNDS WHICH INHIBIT PLATELET AGGREGATION BY INTERACTION WITH THE GPIIB/IIIA RECEPTOR COMPLEX |
摘要 |
This invention provides novel cyclic compounds containing carbocyclic ring systems of formula (I), which are useful as antagonists of the platelet glycoprotein (IIb/IIIa) receptor complex. The present invention also provides pharmaceutical compositions containing such compounds and therapeutic methods of using such compounds and compositions for the inhibition of platelet aggregation, as thrombolytics, and/or for the treatment of other thromboembolic disorders. In said formula, A, B, C, D, E, F, G, H and L are as claimed.
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申请公布号 |
WO9523811(A1) |
申请公布日期 |
1995.09.08 |
申请号 |
WO1995US02572 |
申请日期 |
1995.03.01 |
申请人 |
THE DU PONT MERCK PHARMACEUTICAL COMPANY |
发明人 |
DE GRADO, WILLIAM, FRANK;HOESS, RONALD, HERMAN;JACKSON, SHARON, ANNE;MOUSA, SHAKER, AHMED;O'NEIL, KARYN, THOMPSON;ROCKWELL, ARLENE, LYNNAE |
分类号 |
A61K38/00;C07K7/56;C07K14/75;(IPC1-7):C07K7/56;A61K38/09 |
主分类号 |
A61K38/00 |
代理机构 |
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