XANTHINE DERIVATIVE

摘要

A xanthine derivative represented by general formula (I) or a pharmacologically acceptable salt thereof, wherein R<1>, R<2> and R<3> are the same or different from one another and each represents hydrogen, lower alkyl, lower alkenyl or lower alkynyl; R<4> represents lower alkyl or (un)substituted aryl; R<5> and R<6> are the same or different from each other and each represents hydrogen, lower alkyl or lower alkoxy, or R<5> and R<6> are combined together to represent -O-(CH2)p-O- (wherein p represents an integer of 1 to 3); n represents 0, 1 or 2; and m represents 1 or 2. The compound has an adenosine A2 receptor antagonism and is useful for treating or preventing various diseases caused by the hyperfunctioning of adenosine A2 receptors, such as Parkinson's disease, senile dementia, depression, asthma or osteoporosis.