发明名称 CHOLINESTERASE ACTIVATOR
摘要 The invention relates to a cholinesterase activator comprising, as an active ingredient, a compound represented by the following general formula (I): <IMG> (I) wherein A means a group such as a phenyl group or indanyl group, B denotes a group such as a prolyl group or thioprolyl group, and m stands for an integer of 0-5. The cholinesterase activator according to the invention has a strongly activating action on cholinesterase, in particular, a selectively activating action on peripheral cholinesterase and is also high in safety. It is hence useful as an agent for preventing and treating the side effects of central cholinesterase inhibitors, in particular, hepatopathy, and an agent for preventing and treating the side effects of various medicines manifested on the basis of a cholinesteraseinhibiting action.
申请公布号 CA2182882(A1) 申请公布日期 1995.08.24
申请号 CA19952182882 申请日期 1995.02.17
申请人 发明人 TANAKA, YOSHIAKI;KOBAYASHI, NAOMI;NAKATA, NAOKI;YAMAGUCHI, ITARU;MORI, TADASHI
分类号 C07D277/06;A61K31/40;A61K31/401;A61K31/4025;A61K31/42;A61K31/421;A61K31/425;A61K31/426;A61K31/427;A61K31/4427;A61K31/4439;A61K31/445;A61K31/54;A61P25/00;A61P25/28;A61P43/00;C07D207/08;C07D207/16;C07D211/60;C07D263/06;C07D279/12;C07D401/06;C07D417/06;(IPC1-7):A61K31/54 主分类号 C07D277/06
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