发明名称 |
Substituted [1H-imidazol-5-ylialkanoic acids having angiotension II receptor antagonist activity |
摘要 |
PCT No. PCT/US91/05391 Sec. 371 Date Jan. 29, 1993 Sec. 102(e) Date Jan. 29, 1993 PCT Filed Jul. 30, 1991 PCT Pub. No. WO92/02510 PCT Pub. Date Feb. 20, 1992.Angiotensin II receptor antagonists having the formula: <IMAGE> which are useful in regulating hypertension and in the treatment of congestive heart failure, renal failure, and glaucoma, pharmaceutical compositions including these antagonists, and methods of using these compounds to produce angiotensin II receptor antagonism in mammals.
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申请公布号 |
US5444080(A) |
申请公布日期 |
1995.08.22 |
申请号 |
US19930965291 |
申请日期 |
1993.01.29 |
申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
GIRARD, GERALD R.;HAMPEL, JUDITH;HILL, DAVID T.;SAMANEN, JAMES;WEINSTOCK, JOSEPH |
分类号 |
A61K31/415;A61K31/4164;A61K31/4174;A61K31/4178;A61K31/44;A61K31/4427;A61K31/443;A61K31/4433;A61P9/00;A61P9/12;A61P13/02;A61P15/00;A61P27/02;A61P43/00;C07D233/54;C07D233/60;C07D233/64;C07D233/68;C07D233/70;C07D233/84;C07D233/88;C07D233/91;C07D401/06;C07D401/14;C07D403/04;C07D403/06;C07D403/14;C07D405/06;C07D405/14;C07D409/06;C07D409/14;C07D413/06;C07D413/14;C07D417/06;C07D417/14;(IPC1-7):A61K31/415;C07D403/10 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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