发明名称 Immobilization of Crotalus atrox and Crotalus durissus terrificus whole venoms on aldehyde-activated agarose
摘要 Antivenoms to snake, spider, scorpion and jelly fish venoms are produced for the treatment of humans and animals, and for analytical use. The antivenom is purified with an antigen matrix containing a single whole venom or a plurality of whole venoms covalently attached to an insoluble support such as aldehyde-activated agarose. Preferably, the whole venoms forming the plurality of whole venoms are selected from the four whole venoms from C. atrox, B. atrox, C. adamanteus and C. durissus terrificus. A combination of immobilized C. atrox and C. durissus terrificus whole venoms can substantially purify antivenom reactive with all four venoms. The antivenom can be horse or avian such as chicken antivenom.
申请公布号 US5443976(A) 申请公布日期 1995.08.22
申请号 US19940275304 申请日期 1994.07.14
申请人 CARROLL, SEAN B. 发明人 CARROLL, SEAN B.
分类号 A61K38/00;A61K39/00;A61P31/00;C07K16/02;C07K16/06;C07K16/12;C07K16/18;C07K17/08;(IPC1-7):C12N11/10;C12N11/08;G01N33/544;C07K17/10 主分类号 A61K38/00
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