METHODS FOR AMELIORATION OF IMMUNODEFICIENCY VIRUS INDUCED NEURODEGENERATION BY COVERING NITRIC OXIDE OR SUPEROXIDE CONCENTRATION

摘要

Methods are taught for amelioration of neurodegeneration which accompanies infection with an immunodeficiency virus. Agents are administered which reduce nitric oxide production by neurons (e.g. nitric oxide synthase inhibitors, calmodulin inhibitors, immunophilin binding drugs) or lower superoxide concentration (e.g. superoxide dismutase gene).